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Compact nanosensors probe microdroplets
Julian Schütt, Felix Zörgiebel, Bergoi Ibarlucea, Sebastian Pregl, Daijiro Nozaki, Walter Weber, Thomas Mikolajick. Larysa Baraban and Gianaurelio Cuniberti
DPG Frühjahrstagung der Sektion Kondensierte Materie (SKM)
2016.03.10; Regensburg, Germany
| Smart combination of nanosensors and droplets based reactors represents a powerful tool for monitoring and high throughput analysis of the kinetics of biological and chemical reactions, staying miniaturized, highly sensitive and optically label-free. Here we present a first demonstration of droplets microfluidics with the compact silicon nanowire field effect transistor (SiNW FET) on a single chip for in flow electrical detection of aqueous reactor-drops. Apart from detection events, we chemically probe the content of numerous droplets in a row as independent events (up to ten thousands), and resolve the pH values and ionic strength of the solution, resulted in a change of a source-drain current through the nanowires. Optic-less and noninvasive measurements of these parameters in aqueous droplets have a great impact on the area of biodetection and bioanalytics as a high throughput screening tool for pathogens, drug assays, and evaluation of the enzymatic activities.
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last modified: 2021.04.14 Wed
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Prof. Dr. Gianaurelio Cuniberti
secretariat:
postal address:
Institute for Materials Science
TU Dresden
01062 Dresden, Germany
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