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TU Dresden » Faculty of Mechanical Science and Engineering » Institute for Materials Science » Chair of Materials Science and Nanotechnology

» presentations   » 2017.03.20

Compact Nanowire Sensors Probe Microdroplets

Julian Schütt, Bergoi Ibarlucea, Rico Illing, Felix Zoergiebel, Sebastian Pregl, Daijiro Nozaki, Walter Weber, Thomas Mikolajick, Larysa Baraban, and Gianaurelio Cuniberti

DPG Frühjahrstagung der Sektion Kondensierte Materie (SKM)

2017.03.20; Dresden, Germany

Here we demonstrate a first combination of droplets microfluidics with the compact silicon nanowire field effect transistor (SiNW FET) in the microfluidic channel for in flow electrical detection of aqueous reactor-drops. Apart from detection events, we chemically probe the content of numerous droplets in a row as independent events (up to 104), and resolve the pH values and ionic strength of the solution, resulted in a change of a source-drain current ISD through the nanowires. We demonstrate the capability of the novel droplets based nanowire platform for bioassay applications and carry out a glucose oxidase (GOx) enzymatic test for glucose detection. Optic-less and noninvasive measurements of these parameters in aqueous droplets have a great impact on the area of biodetection and bioanalytics as a HTS tool for pathogens, drug assays, and evaluation of the enzymatic activities.

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