We study the conductance of a single molecule
sandwiched between two electrodes and taking into
account the center of mass motion of the molecule. The
starting point is a tight-binding model Hamiltonian,
which includes a linear coupling between the electronic
degrees of freedom and the bosonic motion. The
conductance is calculated within the scattering matrix
formalism. The coupling to the electronic degrees of
freedom shows the interesting effect such as enhancing
the off resonant conductance.