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SPM and charge transport measurements of various DNA and DNA-based molecules
H. Cohen, C. Nogues, E. Shapir, N. Borovoka, T. Mototskya, J. Yi, R. Naaman, G. Cuniberti, A. Kotlyar, and D. Porath
International Symposium: DNA-based molecular electronics
2004.05.13-15; Jena, Germany
| DNA is considered as one of the attractive candidates
for molecular electronics due to the high density of
its components, its accurate synthesis and its
double-strand recognition properties that suggest
self-assembly. DNA was studied in many ways including:
electrical transport, atomic force microscope (AFM) and
scanning tunneling microscope (STM). It seems that the
results of the various measurements of charge transport
in DNA are not consistent. We have now developed a
method to attach short (26 bp) DNA molecules to a gold
surface at one end and to a gold nanoparticle on the
other end. Upon approaching and contacting the gold
particle with a conductive AFM tip with a controlled
applied force, we can measure current-voltage curves
through the double-stranded DNA molecule. Preliminary
measurements show relatively high currents. We report
also control experiments that are performed on the
insulating surrounding layer. We also report the
production and characterization of novel DNA-based
molecules that may have better conduction properties.
If time allows we will report results of
topography contrast inversion that is observed in STM
imaging of DNA molecules (the DNA appears above the
surface in parts of the image and under it in other
parts). This contrast is induced either spontaneously
or in a controlled way. The results are interpreted and
simulated theoretically as well.  FIGURE: Schematic of
the experiment (a) and a topography image of gold
nanoparticles connected through double-stranded DNA to
an underlying gold surface surrounded by a
single-stranded DNA monolayer.
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Prof. Dr. Gianaurelio Cuniberti
secretariat:
postal address:
Institute for Materials Science
TU Dresden
01062 Dresden, Germany
visitors and courier address:
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