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TU Dresden » Faculty of Mechanical Science and Engineering » Institute for Materials Science » Chair of Materials Science and Nanotechnology

Thursday, 22 October 2009
(at 13:00 in room 115, Hallwachsstr. 3)
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Analyzing emergent behaviour in cellular automaton models of cancer invasion

Andreas Deutsch

The Center for Information Services and High Performance Computing (ZIH)
Dresden University of Technology

Deciphering the principles of tumour growth dynamics is crucial for the development of new therapy concepts. Besides increasingly complex molecular investigations, mathematical modelling and computer simulation of selected aspects of tumour growth have become attractive within the last years. Here, we focus on the analysis of cancer invasion. Lattice-gas cellular automaton (LGCA) models allow for an adequate description of individual invasive cancer cell behaviour (microscopic level). We will show how analysis of the LGCA models allows for prediction of emerging macroscopic properties (in particular of the invasion speed). Furthermore, we will use our models for the interpretation of data from in vitro glioma cell invasion assays.

Brief Bio:

Andreas Deutsch is heading the department "Innovative Methods of Computing" that is devoted to modelling and simulation of biological systems (at the Center for Information Services and High Performance Computing, Technische Universität Dresden). He studied mathematics and biology at the University of Mainz, received his PhD in biology from the University of Bremen, and his habilitation in theoretical biology from the University of Bonn. Research efforts are directed towards theoretical biology with an emphasis on modelling questions of cell and developmental biology as well as tumour growth. A further research field focuses on the exploitation of bio-inspired ideas for the solution of problems in dynamical technical (e.g. logistical) networks. He is author of a monograph on cellular automaton modelling of biological pattern formation (Birkhauser, Boston 2005). Furthermore, Andreas Deutsch was scientific coordinator of the European Conference for Mathematical and Theoretical Biology (ECMTB 2005) in Dresden with more than 900 participants elected board member (treasurer) of the European Society for Mathematical and Theoretical Biology (ESMTB).

slides (pdf)

Invited by G. Cuniberti

last modified: 2018.10.24 Mi
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