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TU Dresden » Faculty of Mechanical Science and Engineering » Institute for Materials Science » Chair of Materials Science and Nanotechnology



Tuesday, 03 May 2016
(at 17:00 in room BIOTEC, seminar rooms E05/E06, Broadcasted from KU Leuven, Belgium)
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Studying nanomedicine bio-barriers by advanced fluorescence microscopy

Prof. Kevin Braeckmans


KU Leuven, Belgium
   






In drug delivery, intensive research is being carried out to develop ‘intelligent’ nanocarriers that are capable of efficiently delivering biopharmaceuticals (nucleic acids, peptides, proteins) to target cells. Advanced fluorescence microscopy methods are indispensable to obtain better insight in the ability of nanomedicines in crossing biological barriers that are of relevance to the drug delivery process. In this lecture, several of these microscopy techniques will be introduced and examples will be given of their application to studying the interaction of nanomedicines with various biological barriers, such as the blood circulation, extracellular tissues as well as cells. It will be illustrated how this knowledge is essential to optimize the design of these nanocarriers in a rational manner in order to increase their drug delivery efficiency.

Brief Bio:

Having obtained a Licentiate degree in Physics at Ghent University (Belgium) in 1999, Kevin Braeckmans joined the Laboratory of General Biochemistry and Physical Pharmacy (Ghent University) to perform research on advanced optical microscopy methods for pharmaceutical applications. During his Ph.D. he was involved in the development of a new type of encoded microcarriers for diagnostic applications, for which he received the first price for Young Biotechnology Researchers from the Funds of Biotechnology (FBBF, Belgium) in 2005. In 2004 he received a post-doctoral fellowship from the Fund for Scientific Research – Flanders, focusing on single particle tracking microscopy. In 2008 he was appointed as professor at Ghent University where he is currently leading the Bio-Photonic Imaging Group in close collaboration with the Ghent Research Group on Nanomedicines (prof. Stefaan De Smedt). His research involves the development and application of microscopy-based methods for studying the interaction of nanomaterials with biological barriers. In 2015 he was awarded an ERC Consolidator Grant (2015-2020) to continue his recent work on light-enabled drug and nanoparticle delivery.

last modified: 2017.11.15 Mi
author: webadmin

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