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TU Dresden » Faculty of Mechanical Science and Engineering » Institute for Materials Science » Chair of Materials Science and Nanotechnology

Thursday, 08 December 2016
(at 13:00 in room 115, Hallwachsstr. 3)
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Electronic Tissue Technologies for Interfacing and Repair of the Nervous System

Dr. Ivan Minev

BIOTEC, TU Dresden

Bioelectronic medicine may soon enable the restoration of body functions lost in injury or disease. This will have high impact in the nervous system, where failure of self-repair following trauma, stroke or neurodegeneration can have profound and permanent consequences on the patient’s quality of life. Implanted systems will deliver, tune and coordinate a therapeutic program consisting of electrical impulses, drugs, light, or replacement cells. The realization of this vision is hindered by the lack of an implantable technology that can blend with the host organ and deliver such complex functionality.
In this talk, I will summarize my experience in building neuroprosthetic implants. I will emphasize on the materials and technologies used for fabricating devices that not only integrate with mechanically delicate neural tissues but also deliver multi-modal neuromodulation. We created an artificial membrane that mimics the mechanical properties of dura mater - the protective skin around the brain and spinal cord - and integrated nanocomposite electrodes, thin-film interconnects and microfluidics to enable its functionality. Chronically implanted on the surface of the spinal cord, the electronic dura mater was used to restore walking in rats with paralyzing spinal cord injury by delivering precise electro-chemical stimulation to the dormant spinal cord [1]. Finally, I will discuss how bioelectronic systems can be harnessed to repair the injury and possibly deliver a permanent therapeutic effect.

Announcement (pdf)

Brief Bio:

Ivan Minev received the MSci degree in Physics from Imperial College London in 2008. He obtained the PhD degree from the Department of Electrical Engineering at the University of Cambridge in 2012. From 2012 to 2016 he was post-doctoral researcher at the Center for Neuroprosthetics in EPFL, the Swiss Federal Institute of Technology in Lausanne.
He has co-organized several symposia on the topic of soft bioelectronics as part of the Materials Research Society Spring Meetings in San Francisco and Phoenix.
In 2016, Ivan received the Freigeist fellowship from the Volkswagen Stiftung and is now leading the “Electronic Tissue Technologies” group at TU Dresden’s BIOTEC center.

Invited by G. Cuniberti

Within the nanoSeminar

last modified: 2021.10.02 Sat
author: webadmin