Droplet microfluidics has proved efficiency in simple manipulating of small volumes of liquid samples, especially in combination with electrochemical means of detection e.g. field-effect transistors, amperometric sensors, impedimetric sensors, etc. The abovementioned
combination has grown in a lab on a chip approach for the detection of various substances. However, the problem of precise droplet manipulation and long-term recirculation over individual sensors is still present. Present work is focused on microfluidic design and the way of liquid control that enables recirculation real-time monitoring of about a hundred droplets with microwire-based impedimetric sensors. The long-term recirculation of droplets over the microwire area can be used for monitoring biochemical reactions whose real-time analysis of the kinetics can be advantageous for a more precise analysis. The combination of circular microfluidics and nanosensors allows long-term recirculation of droplets over the sensor which can be used for monitoring biochemical reactions within solutions or cell/bacteria cultures. The generation of around a hundred droplet reactors provides high reliability and throughput of the result due to statistical reasons, precise flow-rate manipulation allows viability of the assay, and impedimetric way of monitoring provides an immersive analysis of the embedded compounds.
Dmitry completed his bachelor degree in Moscow Institute of Physics and Technology (MIPT) with the specialization on Applied Mathematics and Physics. In 2017 he joined our chair and obtained his MSc degree at TU Dresden. During the master thesis he investigated ithe area of synergy between droplet microfluidics and nanosensorics for label-free bioassays.
In 2017 continued his work as PhD student under Prof. Gianaurelio Cuniberti and worked on development of the technique allowing in-time investigation and detection of chemical and biological substances in droplets using microfluidics and nanosensorics.
Droplet microfluidics has proved efficiency in simple manipulating of small volumes of liquid samples, especially in combination with electrochemical means of detection e.g. field-effect transistors, amperometric sensors, impedimetric sensors, etc. The abovementioned
combination has grown in a lab on a chip approach for the detection of various substances. However, the problem of precise droplet manipulation and long-term recirculation over individual sensors is still present. Present work is focused on microfluidic design and the way of liquid control that enables recirculation real-time monitoring of about a hundred droplets with microwire-based impedimetric sensors. The long-term recirculation of droplets over the microwire area can be used for monitoring biochemical reactions whose real-time analysis of the kinetics can be advantageous for a more precise analysis. The combination of circular microfluidics and nanosensors allows long-term recirculation of droplets over the sensor which can be used for monitoring biochemical reactions within solutions or cell/bacteria cultures. The generation of around a hundred droplet reactors provides high reliability and throughput of the result due to statistical reasons, precise flow-rate manipulation allows viability of the assay, and impedimetric way of monitoring provides an immersive analysis of the embedded compounds.
Dmitry completed his bachelor degree in Moscow Institute of Physics and Technology (MIPT) with the specialization on Applied Mathematics and Physics. In 2017 he joined our chair and obtained his MSc degree at TU Dresden. During the master thesis he investigated ithe area of synergy between droplet microfluidics and nanosensorics for label-free bioassays.
In 2017 continued his work as PhD student under Prof. Gianaurelio Cuniberti and worked on development of the technique allowing in-time investigation and detection of chemical and biological substances in droplets using microfluidics and nanosensorics.
