Biosensing with plasmonic gold nanorod arrays


DPG Frühjahrstagung der Sektion Kondensierte Materie (SKM) | event contribution
March 21, 2017 | Dresden, Germany

Label-free biosensing based on localized surface-plasmon resonances (LSPR) in noble-metal nanostructures has gained a lot of interest in past years. This is mostly due to the possibility of spectral tuning, miniaturization and flexible integration into nanobiotechnological architectures (e.g. microfluidics). Here we report on the fabrication of such a LSPR biosensor based on extended arrays of gold nano-antennas [1,2]. These nanorod carpets are prepared by electro-chemical filling of gold into nanometer-sized pores in an anodized aluminum oxide (AAO) template [3]. The chosen fabrication method [3] allows for a wide range of spectral tunability at visible wavelengths [2], hence facilitating optimized sensor-array performance at the highest sensitivity in the nanomolar range. We demonstrate the feasibility of our approach through monitoring the reproducible binding/unbinding of complementary single-stranded DNA molecules used here as a model system.


Authors

Biosensing with plasmonic gold nanorod arrays


DPG Frühjahrstagung der Sektion Kondensierte Materie (SKM) | event contribution
March 21, 2017 | Dresden, Germany

Label-free biosensing based on localized surface-plasmon resonances (LSPR) in noble-metal nanostructures has gained a lot of interest in past years. This is mostly due to the possibility of spectral tuning, miniaturization and flexible integration into nanobiotechnological architectures (e.g. microfluidics). Here we report on the fabrication of such a LSPR biosensor based on extended arrays of gold nano-antennas [1,2]. These nanorod carpets are prepared by electro-chemical filling of gold into nanometer-sized pores in an anodized aluminum oxide (AAO) template [3]. The chosen fabrication method [3] allows for a wide range of spectral tunability at visible wavelengths [2], hence facilitating optimized sensor-array performance at the highest sensitivity in the nanomolar range. We demonstrate the feasibility of our approach through monitoring the reproducible binding/unbinding of complementary single-stranded DNA molecules used here as a model system.


Authors